Bruce Springsteen has shared an uplifting update about his wife Patti Scialfa, revealing she is now in remission after living with multiple myeloma.

Speaking via a pre-recorded video at the annual Pan-Mass Challenge, a major fundraising bike ride supporting cancer research and treatment at the Dana-Farber Cancer Institute, the 76-year-old also performed an acoustic version of Born to Run.

“We’re a little late, but here we are and it’s a pleasure to be with you,” Springsteen said in the video. “Since 1980, you have inspired a community who has done something remarkable. You’ve never stopped believing that ordinary people can make an extraordinary difference. And because of that countless lives have been saved.”

During the message, the Dancing in the Dark singer revealed Scialfa’s health update, saying she “has been living with her multiple myeloma for over eight years, but now thankfully she is in remission.”

He also reflected on the broader impact of cancer, noting there are “millions of families facing cancer” and stressing the importance of remembering that “hope has a face.”

“It’s our physician who refuses to stop searching and caring, it’s our nurse who sits beside us when we’re scared and always makes our journey just a little bit easier,” he said.

“I’ve spent my life writing songs about the people who keep believing when life gives them every reason not to and for those who refuse to leave someone behind. That’s always been the best of America to Patti and I,” he continued.

“Now, more than ever, the world needs more everyday heroes like the folks who make up the PMC.”

Springsteen first publicly revealed Scialfa’s diagnosis in October 2024 in the documentary Road Diary: Bruce Springsteen and the E Street Band, sharing she had been diagnosed in 2018.

“This affects my immune system so I just have to be careful what I choose to do and where I choose to go,” Scialfa said in the documentary. “Every once in a while, I come to a show or two and I can sing a few songs onstage, and that’s been a treat. That’s the new normal for me right now, and I’m okay with that.”

Later that month, at the documentary’s Los Angeles premiere, Springsteen spoke candidly about how the diagnosis had shaped his outlook.

“Hey, you get up around our age, and those are the things you’re thinking about,” he told the audience. “Patti and I have had to deal with her illness, and you’re worried about... it is a part of your life now, questions of mortality, and it just becomes a part of your life.”

Springsteen and Scialfa, who married in 1991, recently celebrated their 35th wedding anniversary. They share three children: son Evan, daughter Jessica and son Sam.